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hey guys I’m here with Dave Feldman this

guy is awesome he basically is a an

outsider that can take complex subjects

about cholesterol and break them down

for the average person understand and

what I like about you you’re a software

engineer so you actually think in logic

so you basically looked at this problem

from an engineering standpoint you know

and you actually just really figured out

because as you would agree that you

would think there’s a lot of science and

medicine but there’s doesn’t seem to be

a lot of common sense when there comes

to own cholesterol there’s so much

excitement around particular there there

really is a sort of prevailing I I want

to find a better word for this but a

prevailing attitude towards cholesterol

where it’s sort of a almost a near

avoidance of finding good news that

associate suspect cholesterol with

positive outcomes yeah guys if you don’t

know this Dave is going to be at our

summit okay and there’s a couple little

things that we’re gonna tell you right

now that we can’t tell you fully but

there’s potentially gonna be a release

of some new information that’s quite

huge right Dave yes yes hopefully it’ll

be done by that hopefully I mean one of

the things that I think a lot of people

can appreciate is it’s kind of amazing I

always think that I’ve reached an apex

of the data that I’ve gathered both for

my own in of one experiments and those

who follow me and often I’m wrong often

in fact I don’t know of a single time

I’ve been able to give a presentation

where at least 50% of it didn’t have to

change from the last one it’s it’s very

common for me to have a whole lot of new

data and in particular one of the things

that has been a very impressive treasure

trove is this most recent experiment

where I literally gained weight and in

in the current phase of the weight loss

period of that same experiment I haven’t

actually fully lost all of the weights

at a game and from

because this has never actually been

done before Eric and I’m pretty I’m

pretty excited to be able to have done

this is that we’ve never had people

who’ve gone on a low-carb fever genic

diet and throughout the whole process

took very wide spectrum of tests and so

I thought you know I’m I’m gonna go

ahead and just take this shot all the

time insisting that nobody else follow

my shoot there’s a lot of people get

inspired by my experiments but I say

this is the one not to do because in

order to do it you have to induce a

state of hyperinsulinemia I I was adding

of course a lot of carbs and fat and

maintaining at such a level that I would

eventually I was trying to shoot for

gaining about twenty to twenty-five

pounds of fat body fat yeah and and for

what it’s worth you really can do it

pretty quickly because that magic mix

going on particularly with the high

carbs I had my carbs up very very high

and it you know I got 219 pounds up I

didn’t actually get to the 20 to 25 but

I’m okay with that knowing what I know

now I definitely gathered quite a lot it

the primary purpose I was going for

actually came back to cholesterol what I

was trying to do is I was trying to see

as many people see themselves when they

go on this diet and that had much higher

levels of body fat you may actually have

lower relative LDL cholesterol the

so-called bad cholesterol then you do as

you actually lose a lot of weight so I

wanted to both know okay does your LDL

cholesterol go up as you’re losing

weight and also does your LDL tend to be

lower relative to what your LDL

cholesterol would be at when you are at

a lower rate if you say stall

so I actually had hoped to have stalled

right at the top right the peak there so

that I can make that comparison as it

happens I didn’t almost as fast as when

I switched over to congenic diet again

the weight started coming off right away

but I got to answer that one question

which is as ldl-c

indeed go up as you lose weight and I

can share that with you now yes it does

nobody has as pristine a dataset as I do

I literally hit my hundredth blood draw

I want to say a week and a half ago and

in in doing so I have practically a

mapped metabolism like I could I joke

about this but I’m gonna probably do it

at some point I literally could get from

you I could have you write down a number

between 100 and 350 and I could move my

LDL cholesterol to within 20 milligrams

per deciliter of that number in like a

week like I’ve got it mapped out to that

degree without any supplements or

medication off Wow

yeah it’s in a bottom line is without

question they can’t keep this data down

for too long there’s no single larger

influencer on your cholesterol levels

no single larger one then your

metabolism particularly your energy

metabolism and if you’re powered more by

fat then you are powered more by

triglycerides carried in the LDL boats

if you will and those boats eventually

get remodeled to LDL particles now

there’s some individual variability

between those but that’s how I’m able to

accomplish that well the value of that

is that I’ve gotten later into these

phases of experiments to where I could

do this one which is I could say okay

well now that I know what my LDL

cholesterol will be at roughly when I’m

at a lower weight if I already gain

weight I can see what would happen to it

on the way up and I could see what would

happen to it on the way down but why

stop it cholesterol why not also take a

whole bunch of other tests people would

not normally take especially at the

switch off what would be for example my

inflammatory inflammatory markers like

il-6 like ferritin my c-reactive protein

of course like what happens to all of

these is it changes on top of that I got

a lot of physical metrics like for

example I got respiratory quotient as we

actually had the face mask on you’re

actually checking how much you’re

burning sugar versus burning fat so I’ve

got that map down but the most explosive

data that I can also share with you now

it’s been my it’s something called a

carotid

to media thickness test we you yes you

you actually what you do is and you may

already be familiar with this it’s an

ultrasound that you get on the common

carotid arteries on the left and right

side of the neck and I’ve been getting

it about every six months starting and I

want to say mid-2016 so about a year

after I’d started keto and at that time

I was at a very high risk level which

definitely surprised me but with each of

the six months both my left and right

side regressed more and more regressed

so it’s supposed to actually slowly

increase with your age but while I was

here genic I was slowly actually

thinning it on both sides the right side

was thicker and had dropped about a

hundred and fifty nanometers and the

left side was thinner but actually had

dropped another 50 itself and they came

to within one nanometer of each other’s

size by November of last year

Wow okay so here’s where we dropped the

bomb what then happened after I did this

standard American diet experiment right

would it have started moving in the

other direction I certainly was

speculating a lot on that publicly and I

was saying well I wouldn’t be surprised

if it did hopefully it doesn’t do it by

a lot and Eric I’m here to tell you that

it did go by a whole lot it actually

went to the highest on both sides Wow

yeah oh my god fact the right side which

had had 150 drop actually moved up I

want to say a hundred and sixty 170 so

it was technically the highest on that

side and the left side which had had

something like a 40 or 50 nanometer jock

had moved to the highest on its side

crossed 600 for the first time so when I

had been insisting nobody else followed

my suit this high yeah I not only I not

only feel strongly about it now but on

top of that I tell everybody I know hey

you know how you’ve always had like a

relative or you yourself who said hey

I’m gonna take a break from the diet for

the holidays

I say go check out my data here because

I’m gonna tell you I am NOT anxious to

repeat this experiment I why I’m glad I

did all this wide spectrum testing in

the first place and yeah I was just

gonna say guys if you if you didn’t get

what he just said he basically did an

experiment to induce a stroke or heart

attack it didn’t quite happen but limit

to see how far we could push himself and

basically created a thickening of the

walls on the carotid arteries

unbelievable

I will dad 100% concede that had I known

that the thickness of the carotid

arteries was going to climb that much

I’m I might not have done this

experiment at all it’s very possible

what’s a percentage like you said you’re

talking about nanometers but what

percentage increase is that um gosh

that’s that’s I’ve never had it posed to

me that way

I guess you could say on one side it was

about this is really rough math but I’m

gonna say like maybe about 20% and on

the other side I want to say about 25% I

think the thing that’ll matter the most

is per my age and gender I had moved

from the beginning of this up to

November of last year I had moved from a

high risk category to roughly a 20 to

30-percent group or even lower and some

I was even below of 20% and then in just

the six months and most likely from

those last four weeks just before the

test was taken I’d moved from that 20%

low-risk category up to 80 85 % risk

category on the thickness now without

question I am obviously banking on

reducing that success by going fully

ketogenic but here’s the kicker Eric

this cannot be understated this is the

most important thing to take away from

this experiment for all of that time

coming up to November of last year my

LDL cholesterol was 200 milligrams per

deciliter or higher that was the average

my LDL particle count was roughly 2000

or higher right this is this is well

into the 90th percentile levels of

liberal proteins so if if indeed the

literature were correct that that alone

is a risk factor because see IMT this

carotid intima-media thickness that is

commonly considered to be at risk when

you have higher levels of LDL this

flatly flatly disproves this on an end

of one so so on a for a layperson

explain that in laypersons terminology

as far as the validity of going by LDL

verses other tests like well how do you

explain it to someone who doesn’t know

about all this stuff I just that the I

would say that in the literature they

try to find proxies for atherosclerosis

which is the build-up of plaque in the

arteries and that’s the reason they like

the common carotid artery this is this

is a fairly large artery it supplies a

lot of blood especially to the brain and

it oftentimes can show an increasing or

decreasing of thickening suggestive of a

thorough sporadic risk so with that in

mind usually getting a regular test is

is something I certainly recommend

because it gives you a sense of again

it’s not a perfect proxy by any means

but it is a fairly commonly used one in

the studies and it’s one that they’ll

often point to to suggest that level of

risk well obviously it tends to track

with the things were used to being

associated with disease insulin of

course hyperinsulinemia

inflammation chronic inflammation and to

be sure

throughout this experiment I knew I was

creating a state of hyperinsulinemia but

I wasn’t as far as I could tell

chronically inflamed or sick in some

ways some kind of special illness that

might have further influenced it it was

really seemingly from my perspective

just those four weeks of being on a

standard American diet and gaining

weight relatively quickly

that’s that clearly is a cause for

concern now what will be curious is

whether or not it snaps back

as in maybe I see a very large decrease

within you know six months and my next

six much more whether it will decline at

the same rate as it was for the two

years that I was getting it every six

months and if that’s the case that that

should only double down just how much

you want to be careful about going off

diet and gaining a lot of weight

especially cheating right so so then

explain the significance of the LDL you

mentioned that but I want you in simple

terms okay so yes LDL cholesterol again

is commonly referred to as the bad

cholesterol and you’ll hear quite often

as I certainly do in reading the

literature that as that LDL is high and

they they tend to like you to be at

under a hundred milligrams per deciliter

an LDL of 99 or less is what they target

some will say if you’re high-risk you

should be under seventy almost say even

if you’re not a high risk that it’s just

better to be under seventy but I am I’m

at double that through most of my

ketogenic diet on average except for

certain experiments where I’m

intentionally manipulating it and given

that given that I’m at 200 or haider I

would certainly expect that my C IMT

would be thickening at a higher rate if

the literature is correct this also

applies to I know I kind of touched on

LDL particles those are the boats that

carry the LDL cholesterol with them and

that too tends to get looked at and

literature especially in the more

advanced literature where they say you

know you I’m sure you’ve talked about

the small dense versus the big fluffy

particles LDL particles well just the a

lot of lipid ologist today would say

it’s just the total number and you want

that number below 1,000 so if you want

that below a thousand in order to reduce

your risk erotic risk certainly if

you’re like me and running at 2,000 or

higher again well into the 90th

percentile if you were to grab you know

a million random people in the United

States you’re going to find that you

have to be above the 90th percentile to

have that

particle count and to be sure I can’t

say for sure and until I could see you

know post versus pre-medicated and so

forth but all that said without question

I feel that if I went to lipid ology

conference today I said hey what do you

suppose the odds are that somebody can

be running and an LDL cholesterol of

above 200 and I’ll be a particle count

of about 2,000 and that their carotid

intima-media thickness intima-media

thickness would actually be thinning and

kind of tempted to go to lipid ology

conference and place bets to raise money

on my research so that’s incredible

last time I talked to you you talked

about cholesterol and caring

triglycerides in that Seibel vitamins

and I think vitamin E touch in that in

very simple terms so people can just

understand that the LDL is not the bad

guy it’s there to do a purpose I have a

job it has a function your body makes it

my goodness I hope you have a few hours

to spare because it’s two minutes yeah

but the summit you I know you’re gonna

cover everything at the summit in detail

and make it really clear so this is just

a little teaser guys just FYI

absolutely so without question for what

you talked about there’s fat soluble

vitamins a d e and K that are carried by

LDL particles and these these are these

are vitamins your cells need and the

degree of accessibility to your tissues

matters so you find that a lot of people

have very low levels very low levels of

LDL particles the boats that carry these

vitamins they end up having deficiencies

lots of nutrient deficiencies associated

with this because your tissues do in

fact need them but there’s another part

of the story that I find fascinating

it’s rarely talked about allele

particles are a key part of your immune

defense you actually have they’ve

actually found that people who had a

genetic disease and many currently do

today called familial

hypercholesterolemia often abbreviated

to F H F H often ends up being an

advantage towards things like infection

the more LDL particles you have the more

they can help to fight the disease and

that makes sense because they have

antioxidants onboard vitamin E is in

fact an antioxidant and antioxidants

their job is to neutralize free radicals

which are reactive oxygen species so the

more of those you have in play sitting

on the shell of these LDL particles the

phospholipid shell the more capability

you have to neutralize these reactive

oxygen species and so it ends up

becoming a net advantage towards a lot

of this illness particularly in that

fashion so that’s just to I’m just going

to fit in with a third one a third one

is is that you’ll find a lot of people

have an easier time recovering when

they’re on a low-carb high-fat diet and

there’s hopefully gonna be more that I

can talk about with this a little bit

later but particularly for my own

research I find that there’s a drop in

LDL cholesterol and LDL particle count

following extensive and rigorous

exercise on my part and I believe that’s

because as it turns out virtually every

cell in your body has something known as

receptor mediated endocytosis I know

it’s a technical word but basically it

just means it can engulf LDL particles

which makes sense because LDL particles

happen to have lots of phospholipids and

cholesterol which guess what every

membrane of every cell in your body has

as well so they can use those raw

materials for repair and growth and

that’s very important yeah and making

hormones testosterone and so there’s a

couple things that I want to just kind

of end off with so let me just kind of

let’s see you basically there’s a good

chance you’ll be done with some research

that you’ll be able to reveal at the

summit ok there’s good there’s like 80%

chance guys so we’re crossing our

fingers on that one and

so you mentioned something some new data

about weight gain loss experience which

which is kind of covered just now that

yeah you’re talking I all have some new

data on that but I I don’t want to I

don’t want to mention it until I have

the analysis done that’s totally fine

this is top secret information guys

you’re you got to come to summit to

hopefully get it have it be revealed

this is awesome so guys we’re doing a

summer October 13th and 14th in Maryland

it’s going to be at the Gaylord hotel

and you’ll come in Friday night and stay

for the weekend we have about seven or

eight speakers if you include myself

which you will and we’re excited so

Dave’s gonna really cover this topic on

cholesterol which is he’s like a human

guinea pig he does massive amounts of

tests on himself and he tracks

everything he’s meticulous very

organized so he’s gonna be able to

summarize this data which we really

appreciate you going through this so we

don’t have to do do it ourselves

you could just tell us what are the

results yeah yes I’m very excited for

the conference I think it’s gonna be a

lot of fun oh yeah we’re planning it’s

gonna be mind-blowing people are gonna

just it’s going to be one of the biggest

events around so definitely stay tuned

for more information guys definitely

show up I’ll put a link down below if

you haven’t seen the website yet thanks

Dave for coming on and we’ll be seeing

you at the event

thank you proud to me