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the pancreas regulates blood glucose levels  by secreting insulin this hormone is produced  

in the regions of the pancreas known as islets  of langerhans populated mostly with beta cells  

once released from the beta cells insulin  assists glucose entry into different cells  

such as the skeletal muscle cells their membranes  contain insulin receptors which help the  

cells absorb glucose for energy an increase in  carbohydrate intake over time results in excess  

levels of insulin in the blood a condition  known as hyperinsulinemia as a protective  

mechanism from this excess cells will then start  resisting insulin binding to their receptors this  

will inhibit the delivery of glucose in the cell a  condition known as insulin resistance to deal with  

the high glucose levels insulin will turn glucose  into fat which leads to obesity this leads to even  

higher levels of insulin over time the beta cells  get exhausted and reduces the output of insulin  

this imbalance between the high blood glucose  resistance of insulin and lower insulin output  

leads to a variety of health issues over time  the number and volume of eyelids get reduced  

less insulin is released and blood sugars now  rise too much this becomes type 2 diabetes